Dark Matter Antigens: Exploration With Molecular & Cellular Tools

Time: 11:30 am
day: Day One

Details:

Solid tumors can display exotic peptides presented by HLA at their cell that are discovered by mass spectrometry and have characteristics of tumor-specific antigens
Molecular tools can be developed to study their broader expression in cancer cell lines and resected cancer specimens
Cellular tools reveal the suitability of these dark matter antigens as targets for immunotherapy